Cann's Principles of Molecular Virology, 7th Edition - 신간POD상품

No. of pages: 398

Published: February 8, 2023

Imprint: Academic Press

Paperback ISBN: 9780128227848

Description

Cann's Principles of Molecular Virology, Seventh Edition provides an easily accessible introduction to modern virology, presenting principles in a clear and concise manner. The new edition provides the history of virology and the fundamentals of the molecular basis of how viruses work. It discusses the interactions which control the structure of virus particles, the ways viruses infect cells, how viruses replicate themselves, and the consequences and pathogenesis of virus infection for host organisms. This fully updated edition also reflects advances made in the field and includes new content on phage therapy, CRISPR as a phage defense / offense system, new ideas about evolution, and giant viruses. With the addition of ancillary resources, Principles of Molecular Virology, Seventh Edition is an essential foundational reference for academics, graduate students, and advance undergraduates in virology, molecular biology, and microbiology as well as researchers entering virology, infectious disease, and immunology research.

Key Features

Provides a conceptual approach to the principles of molecular virology, with important examples of new advances in virology

Includes new concepts in this edition include coverage of emerging topics and new technologies in viral research like phage therapy, CRISPR as a phage defense / offense system, new ideas about evolution, and giant viruses

Contains updated learning outcomes and further reading for each chapter

Supported by online resources for students and instructors

Readership

Academics and graduate students in virology, molecular biology, and microbiology; Researchers entering virology, infectious disease, and immunology research

Table of Contents

Preface

1. What are viruses, and how were they discovered?

Introduction

The history of the discovery of viruses

References

Recommended Reading

2. Viruses and their particles

Viruses and their particles

Virions

References

Recommended reading

3. Virus origins and genetics

The structure and complexity of virus genomes

Origins of viruses

From what did viruses evolve?

The origins of modern eukaryote viruses

Of ERVs and EVEs

The complexity of virus genomes

Molecular genetics

Virus genetics

The global virome

Epidemiology

Summary

References

Recommended reading

4. Virus genomes and their replication

Overview of virus replication

Entrance into cells and viral genome

replication

Genome replication and gene expression

Assembly of virions

Summary

References

Recommended reading

5. Expression of virus genomes

Expression of genetic information

Virus genome coding strategies

Transcriptional control of expression

Posttranscriptional control of expression

Summary

References

Recommended reading

6. Infection and immunity

Virus infection of prokaryotes

Virus infections of plants

Immune responses to virus infections in animals

Innate immune responses

Adaptive immune responses in vertebrates

RNA interference

Virus-host interactions

The course of virus infections

Prevention and therapy of virus infection

Viruses as therapeutics

Chemotherapy of virus infections

Summary

References

Recommended reading

7. Viral pathogenesis

Mechanisms of cellular injury

Viruses and immunodeficiency

Acquired immunodeficiency syndrome

(AIDS)

Virus-related diseases

Bacteriophages and human disease

Cell transformation by viruses

Cell transformation by retroviruses

Cell transformation by DNA viruses

Viruses and cancer

Summary

References

Recommended reading

8. Panics and pandemics

New, emerging, and re-emerging viruses

Re-emerging viruses

Plant viruses

Novel human viruses

Zoonoses

Biowarfare and bioterrorism

Summary

References

Recommended reading

9. Subviral agents: Deltaviruses and prions

Hepatitis delta virus

Prions

Molecular biology of prions

References

Recommended reading

Appendix 1

Index

About the Author

Edward Rybicki

Dr. Edward Rybicki is a Professor in the Department of Molecular and Cell Biology and Biopharming Research Unit of the University of Cape Town, South Africa. His research interests focus around vaccinology, protein expression, marine viromics, and virus diversity. He has authored two books, co-authored over 120 articles and 19 reviews in peer-reviewed journals, about 20 book chapters, and a number of popular or opinion articles and conference reports. Dr. Rybicki is listed as an inventor on 17 patent families, with around 44 country patents published. He writes educational and study material for the Web like the Electronic Introduction to Molecular Virology as well as via the UCT Open Educational Resources page like the Manual of Online Molecular Biology Techniques, which is extensively used by researchers outside of UCT. He maintains a university-level Virology teaching resource called ViroBlogy, as well as a general public information site called Virology News, runs the International Society for Plant Molecular Farming site, co-curates an information page on aquatic viruses and another on virology and bioinformatics, and tweets on virology topics (and other things) under @edrybicki.

Affiliations and Expertise

Professor, Department of Molecular and Cell Biology and Biopharming Research Unit, University of Cape Town, South Africa