Morphological Mouse Phenotyping, 1st Edition - Anatomy, Histology and Imaging

Morphological Mouse Phenotyping: Anatomy, Histology and Imaging is an atlas of explanatory diagrams and text that guides the reader through normal mouse anatomy, histology, and imaging. The book is targeted for mouse researchers and veterinarian and human pathologists, and presents a complete, integrative description of normal mouse morphology.

Disease animal models are fundamental in research to improve human health. The success of using genetically engineered mice to evaluate molecular disease hypotheses has encouraged the development of massive global projects, making the mouse the most used animal disease model. Laboratory mouse populations are straining the housing capacity of pharmaceutical and biotechnology companies, as well as public research institutions. However, the scientific community lacks sufficient expertise in morphological phenotyping to effectively characterize and validate these animal models. The mouse displays fundamental morphological similarities to humans; however, a mouse is not a man.

Table of Contents

Authors

Dedication

Foreword

Preface

Acknowledgments

List of abbreviations

1: Introduction

   Origin of the Laboratory Mouse

   Anatomical Nomenclature

2: Osteology

   Bones of the Skull and Mandible

   Vertebral Column and Thorax

   Bones of the Thoracic Limbs

   Bones of the Pelvic Limbs

3: Arthrology

   Joints without Articular Cavity

   Joints with Articular Cavity

4: Myology

   Form and Structure of Muscles

   The Skeletal Muscle Fiber

   Comparative Anatomy of Mouse Musculature

5: Digestive tract

   Oral Cavity

   Pharynx and Esophagus

   Stomach

   Intestine

   Liver

6: Respiratory apparatus

   Nasal Cavity

   Larynx

   Trachea

   Lungs

7: Urinary organs

   Kidneys

   Ureter

   Urinary Bladder

   Urethra

8: Male genital organs

   Testicles and Epididymis

   Accessory Genital Glands

   Penis

9: Female genital organs

   Ovaries

   Uterine Tubes

   Uterus

   Vagina

   Vulva and Clitoris

10: Anatomy of development

    Ontogenic Development

    Placenta

11: Circulatory System

    Heart

    Arteries

    Veins

    Lymphatic System

    Blood and Lymph

12: The endocrine glands

    Pancreas

    Adrenal Gland

    Thyroid Glands

    Parathyroid Gland

    Hypophysis

13: Nervous System

    Central Nervous System

    Peripheral Nervous System

14: Eye and related structures

    Eyelids and Lacrimal System

    Eyeball

    Orbit

15: Vestibulocochlear organ

    External Ear

    Middle Ear

    Internal Ear

16: Common integument

    Skin

    Modified Skin Structures

Bibliography

Index

About the Author

Jesus Ruberte